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Article

Causal association among glaucoma, cerebral cortical structures, and Alzheimer's disease: insights from genetic correlation and Mendelian randomization.

Cerebral cortex (New York, N.Y. : 1991) - 3 Sept 2024

Chen Jiawei, Zhou Xiaoyu, Yuan Xiang-Ling, Xu Jiahao, Zhang Xinyue, Duan Xuanchu

Abstract excerpt

Glaucoma and Alzheimer's disease are critical degenerative neuropathies with global impact. Previous studies have indicated that glaucomatous damage could extend beyond ocular structures, leading to brain alterations potentially associated with Alzheimer's disease risk. This study aimed to explore the causal associations among glaucoma, brain alterations, and Alzheimer's disease. We conducted a comprehensive...

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Identifiers

PMID: 39323397
DOI: 10.1093/cercor/bhae385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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