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Article

Association of HLA-B*5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis.

BMC medical genetics - 9 Sept 2011

Somkrua Ratchadaporn, Eickman Elizabeth E, Saokaew Surasak, Lohitnavy Manupat, Chaiyakunapruk Nathorn

Abstract excerpt

BACKGROUND: Despite some studies suggesting a possible association between human leukocyte antigen, HLA-B*5801 and allopurinol induced Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), the evidence of association and its magnitude remain inconclusive. This study aims to systematically review and meta-analyze the association between HLA-B*5801 allele and allopurinol-induced SJS/TEN. METHODS: A...

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Identifiers

PMID: 21906289
DOI: 10.1186/1471-2350-12-118
PMCID: PMC3189112

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of HLA-B*5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis.PMID 21906289Read ↗

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