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Article

HLA-B*58: 01 association in allopurinol-induced severe cutaneous adverse reactions: the implication of ethnicity and clinical phenotypes in multiethnic Malaysia.

Pharmacogenetics and genomics - 1 Sept 2020

Low Dyoi E, Nurul-Aain Ahmad Fauzi, Tan Wooi Chiang, Tang Jyh Jong, Bakhtiar Mohammed Faizal, Murad Shahnaz, Chang Choong Chor, Too Chun Lai, Tang Min Moon

Abstract excerpt

OBJECTIVE: The association between human leukocyte antigen (HLA)-B*58:01 and risk of allopurinol-induced severe cutaneous adverse reactions (AIS) was observed across different populations. We explore the association between HLA-B*58:01 and AIS risk in multiethnic Malaysian population. The HLA-B*58:01 risk for different AIS clinical phenotypes and ethnicity was determined. METHODS: We performed a case-control...

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Identifiers

PMID: 32433341
DOI: 10.1097/FPC.0000000000000408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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