Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

Abstract excerpt

<title>Abstract</title> <p>A multitude of tools now exist that allow us to precisely manipulate the human genome in a myriad of different ways. However, successful delivery of these tools to the cells of human patients remains a major barrier to their clinical implementation. Here we introduce a new cellular approach for in vivo genetic engineering, Secreted Particle Information Transfer (SPIT) that utilizes huma...

Topics

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• CAR-T cell therapy research
• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Gene Editing
• Gene Transfer Techniques
• Genetic Predisposition to Disease
• RNA Interference and Gene Delivery
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

bf4a411e-3064-5da2-bec1-2b5911580f99

DOI

10.21203/rs.3.rs-4810212/v1