Delivering genes with human immunodeficiency virus-derived vehicles: still state-of-the-art after 25 years

Abstract excerpt

Viruses are naturally endowed with the capacity to transfer genetic material between cells. Following early skepticism, engineered viruses have been used to transfer genetic information into thousands of patients, and genetic therapies are currently attracting large investments. Despite challenges and severe adverse effects along the way, optimized technologies and improved manufacturing processes are driving...

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