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Recent challenges and advances in genetically-engineered cell therapy

28 Dec 2017

Abstract excerpt

Cells naturally sense and actively response to their environment. Cell-therapy has long been studied and shown therapeutic effects in various diseases. However, several hurdles should be overcome to improve cell-based therapy. Gene delivery-mediated cellular modification has shown improvement of cell function by obstacle gene silencing and therapeutic gene expression. Especially, CRISPR/Cas9-mediated genome...

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PMID: 30680249
DOI: 10.1007/s40005-017-0381-1

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