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Article

Immune gene diversity in archaic and present-day humans

2018-06-16

Abstract excerpt

Genome-wide analyses of two Neandertals and a Denisovan have shown that these archaic humans had lower genetic heterozygosity than present-day people. A similar reduction in genetic diversity of protein-coding genes ( gene diversity ) was found in exome sequences of three Neandertals. Reduced gene diversity, and particularly in genes involved in immunity, may have important functional consequences. In fact, it ha...

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Literature Corpus work
bf1f2756-e4d5-5aa3-8861-bd017d3b9dc6
DOI
10.1101/348581
Open publication

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Immune gene diversity in archaic and present-day humansDOI 10.1101/348581
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