Article

DynPerturb:Dynamic Perturbation Modeling for Spatiotemporal Single-Cell Systems

2025-09-18

Abstract excerpt

Perturbation responses in multicellular systems are inherently spatiotemporal, governed by temporal dynamics, perturbation intensity, and tissue context. However, existing approaches rarely capture explicit spatiotemporal perturbation dynamics, limiting the ability to reconstruct how perturbations propagate over time, spread across space, and induce feedback at multiple biological scales. Here we introduce DynPert...

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Literature Corpus work: bef51f51-a299-50a7-86a3-0e1fc8b63174
DOI: 10.1101/2025.09.15.676236

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