Article

Charting spatial ligand-target activity using Renoir

2023-04-17

Abstract excerpt

The advancement of single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics has enabled the inference of cellular interactions in a tissue microenvironment. Despite the development of cell-cell interaction inference methods, there is a lack of methods capable of mapping the influence of ligands on downstream target genes across a spatial topology with specific cell type composition, with the potential to...

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Literature Corpus work: 77d0b362-63d7-5205-9d6a-9bb3d4e4dff1
DOI: 10.1101/2023.04.14.536833

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