Article

Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction

2018-11-19

Abstract excerpt

<h4>ABSTRACT</h4> Thermostable group II intron reverse transcriptases (TGIRTs) with high fidelity and processivity have been used for a variety of RNA sequencing (RNA-seq) applications, including comprehensive profiling of whole-cell, exosomal, and human plasma RNAs; quantitative tRNA-seq based on the ability of TGIRT enzymes to give full-length reads of tRNAs and other structured small ncRNAs; high-throughput ma...

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Literature Corpus work: 0e535d96-eaf6-5141-83e5-0aa7138c8c29
DOI: 10.1101/474031

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