Article
Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes.
Nature communications - 27 Nov 2017
Burguera Demian, Marquez Yamile, Racioppi Claudia, Permanyer Jon, Torres-Méndez Antonio, Esposito Rosaria, Albuixech-Crespo Beatriz, Fanlo Lucía, D'Agostino Ylenia, Gohr Andre, Navas-Perez Enrique, Riesgo Ana, Cuomo Claudia, Benvenuto Giovanna, Christiaen Lionel A, Martí Elisa, D'Aniello Salvatore, Spagnuolo Antonietta, Ristoratore Filomena, Arnone Maria Ina, Garcia-Fernàndez Jordi, Irimia Manuel
Abstract excerpt
Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how molecular tools are recruited in different lineages to control interplays between these tissues is key to understanding morphogenetic evolution. Here, we study Esrp genes, which regulate extensive splicing programs and are essential for mammalian organogenesis. We find that Esrp homologs have...
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