Article

Local genetic covariance between serum urate and kidney function obtained from local Bayesian regressions

2021-04-05

Abstract excerpt

Hyperuricemia is associated with several cardiometabolic and renal diseases, such as gout and chronic kidney disease. Previous studies have examined the shared genetic basis of chronic kidney disease and hyperuricemia either using single-variant tests or estimating whole-genome genetic correlations between the traits. Individual variants typically explain a small fraction of the genetic correlation between traits,...

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Literature Corpus work: beb8e3a9-8195-50f3-8639-04c77fe0cef3
DOI: 10.1101/2021.03.31.21254729

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