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Article

GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans.

BMC genomics - 2 Apr 2016

Chittoor Geetha, Kent Jack W, Almeida Marcio, Puppala Sobha, Farook Vidya S, Cole Shelley A, Haack Karin, Göring Harald H H, MacCluer Jean W, Curran Joanne E, Carless Melanie A, Johnson Matthew P, Moses Eric K, Almasy Laura, Mahaney Michael C, Lehman Donna M, Duggirala Ravindranath, Comuzzie Anthony G, Blangero John, Voruganti Venkata Saroja

Abstract excerpt

BACKGROUND: The variation in serum uric acid concentrations is under significant genetic influence. Elevated SUA concentrations have been linked to increased risk for gout, kidney stones, chronic kidney disease, and cardiovascular disease whereas reduced serum uric acid concentrations have been linked to multiple sclerosis, Parkinson's disease and Alzheimer's disease. Previously, we identified a novel locus on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Inositol 1,4,5-Trisphosphate Receptors

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Source

Open in PubMed Open full text

Identifiers

PMID: 27039371
DOI: 10.1186/s12864-016-2594-5
PMCID: PMC4818944

Genes

ITPR1
CNTN4
ARHGEF26
TGM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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