Article

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

2019-11-28

Abstract excerpt

Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unknown. Recently, we identified CD300lf as a proteinaceous receptor for MNoV. Interestingly, its paralogue CD300ld was also sufficient for MNoV infection in vitro . Her...

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Literature Corpus work: be8e225f-c39b-5d9f-971f-02dfb3566a3e
DOI: 10.1101/859025

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