Article
Functional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells.
Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 2016
Haga Kei, Fujimoto Akira, Takai-Todaka Reiko, Miki Motohiro, Doan Yen Hai, Murakami Kosuke, Yokoyama Masaru, Murata Kazuyoshi, Nakanishi Akira, Katayama Kazuhiko
Abstract excerpt
Norovirus is the leading cause of acute gastroenteritis worldwide. Since the discovery of human norovirus (HuNoV), an efficient and reproducible norovirus replication system has not been established in cultured cells. Although limited amounts of virus particles can be produced when the HuNoV genome is directly transfected into cells, the HuNoV cycle of infection has not been successfully reproduced in any...
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