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Article

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of neurological function and disease

2018-09-29

Abstract excerpt

Integrative approaches which harness large-scale molecular datasets can help develop mechanistic insight into findings from genome-wide association studies (GWAS). We have performed extensive analyses to uncover transcriptional and epigenetic processes which may play a role in neurological trait variation. This was undertaken by applying Bayesian multiple-trait colocalization systematically across the genome to id...

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Literature Corpus work
be7aa008-4206-5f80-a1a5-cb218b5474ab
DOI
10.1101/429134
Open publication

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Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of neurological function and diseaseDOI 10.1101/429134
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