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Article

Nanolipoprotein mediated Her2 protein transfection induces malignant transformation in human breast acinar cultures

2020-08-25

Abstract excerpt

Her2 overexpression is associated with an aggressive form of breast cancer and malignant transformation. We sought to determine if a nano-carrier system could introduce Her2 protein to non-malignant cells and determine the effects on cell phenotype and transcriptome. With stimulation with Her2-NLPs, we observed uptake of Her2 protein and a decreased probability of individual non-malignant cells forming polar growt...

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Literature Corpus work
be7422d1-3476-5641-9dca-1d83ecbba18a
DOI
10.1101/2020.08.25.265512
Open publication

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Nanolipoprotein mediated Her2 protein transfection induces malignant transformation in human breast acinar culturesDOI 10.1101/2020.08.25.265512
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