Article
The ultrastructure of MCF-10A acini.
Journal of cellular physiology - 1 Jul 2006
Underwood Jean M, Imbalzano Karen M, Weaver Valerie M, Fischer Andrew H, Imbalzano Anthony N, Nickerson Jeffrey A
Abstract excerpt
MCF-10A human mammary epithelial cells cultured inside reconstituted basement membrane form acini that resemble the acinar structures of mammary lobules. This three-dimensional culture system has been used for identifying and characterizing the signal transduction pathways controlling cell proliferation and death, and for studying their disregulation in malignant progression. We have compared the ultrastructure...
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