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Computational modelling of schizophrenia-associated alterations of ion-channel-encoding gene expression predicts a decrease in delta power

2025-10-20

Abstract excerpt

Schizophrenia presents with a wide range of phenotypes that can help to understand the the mechanisms of the disease. Among these, alterations in delta oscillations are especially amenable to experimental investigation, yet the mechanisms underlying these changes remain insufficiently understood. Biophysically detailed computational modeling offers a powerful approach to investigate these phenomena, as it enables...

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Literature Corpus work
be4d57e4-f532-5768-9f60-bb86e288ce75
DOI
10.1101/2025.10.20.683062
Open publication

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Computational modelling of schizophrenia-associated alterations of ion-channel-encoding gene expression predicts a decrease in delta powerDOI 10.1101/2025.10.20.683062
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