Article

Bridging the scales: leveraging personalized disease models and deep phenotyping to dissect cognitive impairment in schizophrenia

2025-02-27

Abstract excerpt

Schizophrenia (SCZ) is a highly heritable brain disorder marked by a wide range of changes throughout the central nervous system. These changes include alterations at the molecular and cellular levels, suggesting significant disruptions in synapse function, as well as modifications in brain structure and activity. However, it remains unclear, how changes in molecular synapse biology translate into neurophysiologic...

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Literature Corpus work: c95564de-ab1d-537a-9515-bbed32050033
DOI: 10.1101/2025.02.25.25322779

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