Article

<i>In silico</i> hippocampal modeling for multi-target pharmacotherapy in schizophrenia

2019-09-05

Abstract excerpt

<h4>Background</h4> Treatment of schizophrenia has had limited success in treating core cognitive symptoms. The evidence of multi-gene involvement suggests that multi-target therapy may be needed. Meanwhile, the complexity of schizophrenia pathophysiology and psychopathology, coupled with the species-specificity of much of the symptomatology, places limits on analysis via animal models, in vitro assays, and pati...

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Literature Corpus work: 1f8ea6ce-3942-5384-88d7-94d618fe04ab
DOI: 10.1101/758466

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