Article

A computational framework linking molecular regulation, synaptic plasticity, and brain disorders

2025-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Neuroplasticity supports learning, development, and adaptive behavior, but also underlies maladaptive circuit remodeling in neuropsychiatric disorders. Although genetic disruptions of synaptic signaling are widely implicated in these conditions, the causal chain from molecular perturbation to systems-level dysfunction remains unclear. Here we introduce a multiscale computational framework—a para...

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Literature Corpus work: 45604634-b142-5ca5-9a22-feff209730ab
DOI: 10.1101/2025.04.07.647510

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