Article

Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique

2021-05-04

Abstract excerpt

Pseudouridine (Ψ) is the most common non-canonical ribonucleoside present on mammalian non-coding RNAs (ncRNAs), including rRNAs, tRNAs and snRNAs, where it contributes ∼7% of the total uridine level. However, Ψ constitutes only ∼0.1% of the uridines present on mRNAs and its effect on mRNA function remains unclear. Ψ residues have been shown to inhibit the detection of exogenous RNA transcripts by host innate immu...

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Literature Corpus work: be449f0c-f51c-5041-aa60-01e658c192b2
DOI: 10.1101/2021.05.01.442255

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