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Article

RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.

RNA biology - 1 Jan 2014

Yu Yi-Tao, Meier U Thomas

Abstract excerpt

Box H/ACA ribonucleoproteins (RNPs), each consisting of one unique guide RNA and 4 common core proteins, constitute a family of complex enzymes that catalyze, in an RNA-guided manner, the isomerization of uridines to pseudouridines (Ψs) in RNAs, a reaction known as pseudouridylation. Over the years, box H/ACA RNPs have been extensively studied revealing many important aspects of these RNA modifying machines. In...

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Identifiers

PMID: 25590339
DOI: 10.4161/15476286.2014.972855
PMCID: PMC4615163

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Source receipt: pubmed, retrieved 7 Sept 2026.

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