Article

DNA processing by the Kaposi’s sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production

2022-09-19

Abstract excerpt

Alkaline exonucleases (AE) are present in several large DNA viruses including bacteriophage λ and herpesviruses, where they play roles in viral DNA processing during genome replication. Given the genetic conservation of AEs across viruses infecting different kingdoms of life, these enzymes likely assume central roles in the lifecycles of viruses where they have yet to be well characterized. Here, we applied a stru...

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Literature Corpus work: be24e5e0-eb12-5fb8-add6-65b8d96a7331
DOI: 10.1101/2022.09.19.508573

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