Article

A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens

2021-03-29

Abstract excerpt

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern. For more than five decades, the search for new antibiotics has relied heavily upon the chemical modification of natural products (semi-synthesis), a method ill-equipped to combat rapidly evolving resistance threats. Semi-synthetic modifications are typically of limited scope within pol...

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Literature Corpus work: 3717cfe3-be88-5a6d-a6e3-e9d99738cd96
DOI: 10.26434/chemrxiv.14331407.v1

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