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Reduced levels of inositol hexakisphosphate kinase (IP6K) impair life-cycle transitions and the intracellular development of <i>Trypanosoma cruzi</i> within human cardiomyocytes

2026-01-21

Abstract excerpt

Trypanosoma cruzi is the etiological agent of Chagas disease. During its life cycle, T. cruzi undergoes several key differentiation processes that are essential for its survival. The precise mechanisms that regulate these processes remain elusive, and any interference in this cycle would represent a breakthrough in the development of effective therapy against Chagas disease. Here, after depleting a single IP6K a...

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Literature Corpus work
bdd8c878-e353-5f71-9332-8edb4ec1938c
DOI
10.64898/2026.01.21.700787
Open publication

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Reduced levels of inositol hexakisphosphate kinase (IP6K) impair life-cycle transitions and the intracellular development of <i>Trypanosoma cruzi</i> within human cardiomyocytesDOI 10.64898/2026.01.21.700787
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