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Quantitative proteomics of <i>Trypanosoma cruzi</i> during metacyclogenesis

4 Jul 2012

Abstract excerpt

Trypanosoma cruzi is the etiologic agent of Chagas disease, which is estimated to affect over eight million people around the world. Trypanosoma cruzi has a complex life cycle, involving insect and mammalian hosts and four distinct developmental stages: epimastigotes, metacyclic trypomastigotes, amastigotes, and bloodstream trypomastigotes. Metacyclogenesis is the process by which T. cruzi epimastigotes...

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PMID: 22761176
DOI: 10.1002/pmic.201200078

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