Article

Calcium ions trigger the exposure of phosphatidylserine on the surface of necrotic cells

2020-08-21

Abstract excerpt

Intracellular Ca 2+ level is under strict regulation through calcium channels and intracellular Ca 2+ storage pools such as the endoplasmic reticulum (ER). Mutations in certain ion channel subunits, which result in the mis-regulation of Ca 2+ influx, cause the excitotoxic necrosis of neurons. In the nematode Caenorhabditis elegans , six mechanosensory (touch) neurons are induced to undergo excitotoxic necrosis...

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Literature Corpus work: bdb05ce9-1bfa-520b-a2b6-999ce3df3947
DOI: 10.1101/2020.08.21.260695

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