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Article

A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans.

Nature cell biology - 1 Dec 2000

Chung S, Gumienny T L, Hengartner M O, Driscoll M

Abstract excerpt

Similar to mammalian excitotoxic cell death, necrotic-like cell death (NCD) in Caenorhabditis elegans can be initiated by hyperactive ion channels. Here we investigate the requirements for genes that execute and regulate programmed cell death (PCD) in necrotic-like neuronal death caused by a toxic MEC-4 channel. Neither the kinetics of necrosis onset nor the total number of necrotic corpses generated is altered...

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Identifiers

PMID: 11146658
DOI: 10.1038/35046585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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