Article

CD8 <sup>+</sup> T cell immunity is compromised by anti-CD20 treatment and rescued by IL-17A

2019-05-20

Abstract excerpt

Treatment with anti-CD20, used in many diseases in which B cells play a pathogenic role, has been associated with susceptibility to intracellular infections. Here, we studied the effect of anti-CD20 injection on CD8 + T cell immunity using an experimental model of Trypanosoma cruzi infection, in which CD8 + T cells play a pivotal role. C57BL/6 mice were treated with anti-CD20 for B cell depletion prior to T. c...

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Literature Corpus work: bd79fabe-6265-5365-8c59-0ecfa4665cee
DOI: 10.1101/642801

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