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Selective Immune Silencing by Targeted TGF-β Agonists

2026-01-20

Abstract excerpt

Depletion of pathogenic T and B cells is a pillar of first-line therapies for inflammatory, autoimmune, and transplantation-related immunological diseases. However, concerns about adverse events, safety in immunocompromised patients, and disease relapse from incomplete depletion, limit clinical utility. Here, we exploit the immunosuppressive properties of Transforming growth factor beta (TGF-β), through selective...

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Literature Corpus work
036029b9-9aeb-5a09-8751-c9d5780bed42
DOI
10.64898/2026.01.19.700410
Open publication

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Selective Immune Silencing by Targeted TGF-β AgonistsDOI 10.64898/2026.01.19.700410
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