Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses.

Immunity - 1 May 2008

Yanaba Koichi, Bouaziz Jean-David, Haas Karen M, Poe Jonathan C, Fujimoto Manabu, Tedder Thomas F

Abstract excerpt

B cells mediate multiple functions that influence immune and inflammatory responses. In this study, T cell-mediated inflammation was exaggerated in CD19-deficient (Cd19(-/-)) mice and wild-type mice depleted of CD20(+) B cells, whereas inflammation was substantially reduced in mice with hyperactive B cells as a result of CD19 overexpression (hCD19Tg). These inflammatory responses were negatively regulated by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD1
Share to Antigens, CD1d

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B-Lymphocyte Subsets

Share to CD5 Antigens

Share to Interleukin-10

Share to Lymphocyte Depletion

Share to Peritoneal Cavity

Share to Spleen

Source

Identifiers

PMID: 18482568
DOI: 10.1016/j.immuni.2008.03.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses.PMID 18482568Read ↗

Altered Phenotype and Enhanced Antibody-Producing Ability of Peripheral B Cells in Mice with Cd19-Driven Cre Expression.Semantic proximity Read ↗

Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.Semantic proximity Read ↗

B10 Cells: A Functionally Defined Regulatory B Cell SubsetSemantic proximity Read ↗

CD20 <sup>+</sup> T cells are associated with inflammatory responses in experimental arthritisSemantic proximity Read ↗

CD19 expression in B cells is important for suppression of contact hypersensitivity.Semantic proximity Read ↗

Peripheral CD19hi B cells exhibit activated phenotype and functionality in promoting IgG and IgM production in human autoimmune diseases.Semantic proximity Read ↗

Transcriptomics Identify CD9 as a Marker of Murine IL-10-Competent Regulatory B CellsSemantic proximity Read ↗

B10 cell regulation of health and disease.Semantic proximity Read ↗

B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae.Semantic proximity Read ↗

Blimp-1 Contributes to the Development and Function of Regulatory B CellsSemantic proximity Read ↗

The role of B regulatory (B10) cells in inflammatory disorders and their potential as therapeutic targetsSemantic proximity Read ↗

The HMGB1 (C106A) mutation inhibits IL-10-producing CD19hiFcγRIIbhi B cell expansion by suppressing STAT3 activation in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.