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Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation

6 Jul 2015

Abstract excerpt

Protozoan parasites of the genus Leishmania are the etiological agents of leishmaniasis, a group of diseases with a worldwide incidence of 0.9-1.6 million cases per year. We used RNA-seq to conduct a high-resolution transcriptomic analysis of the global changes in gene expression and RNA processing events that occur as L. major transforms from non-infective procyclic promastigotes to infective metacyclic...

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PMID: 26150419
DOI: 10.1093/nar/gkv656

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