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The Genome of the Kinetoplastid Parasite, <i>Leishmania major</i>

14 Jul 2005

Abstract excerpt

Leishmania species cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA genes, 39 pseudogenes, and 8272 protein-coding genes, of which 36% can be ascribed a putative function. These include genes involved in host-pathogen interactions, such as...

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PMID: 16020728
DOI: 10.1126/science.1112680

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