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Genome-wide mapping of RPA1 and RAD9 reveals the management of polycistronic transcription, replication initiation, and responses to replication stress in <i>Leishmania</i>

2024-11-04

Abstract excerpt

When exposed single-stranded DNA accumulates at stalled or collapsed replication forks, the replication stress response is triggered to prevent genome instability. Leishmania are parasitic eukaryotes where gene expression is universally polycistronic and whose plastic genomes facilitate rapid adaptations in response to stress, with evidence implicating intrinsic replication stress as a source. Little is known abo...

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Literature Corpus work
ebedfec5-09fd-5b7f-a5ce-6f488c3b6c95
DOI
10.1101/2024.11.04.621868
Open publication

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Genome-wide mapping of RPA1 and RAD9 reveals the management of polycistronic transcription, replication initiation, and responses to replication stress in <i>Leishmania</i>DOI 10.1101/2024.11.04.621868
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