Article

NAG-1/GDF15 Exerts Anti-diabetic Effects through the Insulin Signaling Pathway

2021-03-01

Abstract excerpt

Nonsteroidal anti-inflammatory drug-activated gene-1 (NAG-1) has a role in various diseases. Here, the anti-diabetic effects of NAG-1 were evaluated using a high-fat diet (HFD)/streptozotocin (STZ)-induced diabetic mouse model. NAG-1-overexpressing transgenic (NAG-1 Tg) mice exhibited lower bodyweight and fasting blood glucose and insulin levels than wildtype (WT) mice. The homeostatic model assessment of insulin...

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Literature Corpus work: bd65eb25-1159-54e1-a210-dbd23961ce53
DOI: 10.21203/rs.3.rs-257216/v1

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