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Article

High Mobility Group Box-1: A Missing Link between Diabetes and Its Complications

1 Jan 2016

Abstract excerpt

High mobility group box-1 (HMGB-1), a damage-associated molecular pattern, can be actively or passively released from various cells under different conditions and plays a pivotal role in the pathogenesis of inflammation and angiogenesis-dependent diseases. More and more evidence suggests that inflammation, in addition to its role in progression of diabetes, also promotes initiation and development of diabetic...

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PMID: 27847406
DOI: 10.1155/2016/3896147

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