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Article

Downregulated NLRP3 and NLRP1 inflammasomes signaling pathways in the development and progression of type 1 diabetes mellitus

5 Aug 2017

Abstract excerpt

Background NLRP3 and NLRP1 inflammasomes signaling pathways may play an important role in the development and progression of type 1 diabetes mellitus (T1DM). However, relative research is rare. Methods The blood mononuclear cells (PBMCs) and granulocytes (GCs) were collected from T1DM patients. The mRNA and protein expression levels were detected by qRT-PCR and Western blotting, respectively. The NLRP3/NLRP1was...

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Share to Diabetes and associated disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28783585
DOI: 10.1016/j.biopha.2017.07.102

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