Article

Calcium-Regulated Mitochondria Remodeling by Myo19 is Required for Filopodia Tip-Extension

2025-10-06

Abstract excerpt

<h4>SUMMARY</h4> Mitochondria are highly adaptable organelles that change their shape, distribution, and movement to meet cellular needs. We investigate how EGF stimulation remodels mitochondrial behavior in human A431 carcinoma cells, where EGF suppresses proliferation but enhances calcium signaling and cell motility. EGF triggers mitochondrial fission, resulting in smaller, more mobile mitochondria that relocat...

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Literature Corpus work: cd33ded3-c4b9-5ac7-b392-8511d6530b76
DOI: 10.1101/2025.10.04.680418

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