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The roles of MKI67, GNL2, and MDN1 in Ribosome biogenesis and Transcriptome regulation in the Neuronal Lineage cell line HEK293T

2025-02-16

Abstract excerpt

Ki-67, a protein encoded by the MKI67 gene, is present in proliferating human tissue cells. It is an important marker for diagnosing cancer. Despite numerous investigations, the function of Ki-67 remains unclear. In this study, we examined the role of Ki-67 and its associated proteins, GNL2 and MDN1, in the HEK293T neuronal lineage cell line using ChIP-seq, RNA-seq, confocal microscopy, and biochemical methods. K...

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Identifiers and source

Literature Corpus work
1a39492c-4ef6-5f5f-a06e-3225ba271249
DOI
10.1101/2025.02.13.638155
Open publication

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The roles of MKI67, GNL2, and MDN1 in Ribosome biogenesis and Transcriptome regulation in the Neuronal Lineage cell line HEK293TDOI 10.1101/2025.02.13.638155
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