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Article

Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.

The Journal of cell biology - 28 Oct 2013

Lázaro-Diéguez Francisco, Cohen David, Fernandez Dawn, Hodgson Louis, van Ijzendoorn Sven C D, Müsch Anne

Abstract excerpt

Columnar epithelia establish their luminal domains and their mitotic spindles parallel to the basal surface and undergo symmetric cell divisions in which the cleavage furrow bisects the apical domain. Hepatocyte lumina interrupt the lateral domain of neighboring cells perpendicular to two basal domains and their cleavage furrow rarely bifurcates the luminal domains. We determine that the serine/threonine kinase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24165937
DOI: 10.1083/jcb.201303013
PMCID: PMC3812971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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