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Article

Characterization of the impact of daclizumab beta on circulating natural killer cells by mass cytometry

2019-12-05

Abstract excerpt

Daclizumab beta is a humanized monoclonal antibody that binds to CD25 and selectively inhibits high-affinity IL-2 receptor signaling. As a former treatment for relapsing forms of multiple sclerosis (RMS), daclizumab beta induces robust expansion of the CD56 bright subpopulation of NK cells that is correlated with the drug’s therapeutic effects. As NK cells represent a heterogeneous population of lymphocytes with...

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Literature Corpus work
bd3a3c77-09f3-50b1-bc80-3f79bc5dbf62
DOI
10.1101/865477
Open publication

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Characterization of the impact of daclizumab beta on circulating natural killer cells by mass cytometryDOI 10.1101/865477
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