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Article

Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting.

Arthritis research & therapy - 15 Sept 2016

Merkt Wolfgang, Lorenz Hanns-Martin, Watzl Carsten

Abstract excerpt

BACKGROUND: Rituximab has broad and increasing application in rheumatic diseases. It is known from lymphoma studies that natural killer (NK) cells can lyse rituximab-coated transformed B cells. However, the role of NK cells in mediating rituximab-induced depletion of non-malignant B cells is unknown. The purpose of this study was to provide fundamental data on rituximab-mediated effects on NK cells in PBMCs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27629249
DOI: 10.1186/s13075-016-1101-3
PMCID: PMC5024429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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