Article
Adalimumab-Induced Changes in NK Cells Phenotype, Receptors, and Functions After Clinical Remission of Behçet's Uveitis.
American journal of ophthalmology - 1 Apr 2026
Esen Fehim, Kokoglu Aysenur, Cetin Cigdem, Turkyilmaz Ozlem, Ceylan Nihan Aksu, Oray Merih, Direskeneli Haner, Tugal-Tutkun Ilknur, Gul Ahmet, Deniz Gunnur, Aktas Cetin Esin
Abstract excerpt
OBJECTIVE: To elucidate adalimumab's mechanism of action in two class-I MHC-associated diseases by characterizing NK cell phenotype and function in Behçet's uveitis (BU) and axial ankylosing spondylitis (AS). DESIGN: Prospective clinical cohort with repeated measures (baseline and month 3). SUBJECTS, PARTICIPANTS, AND/OR CONTROLS: BU (n = 14, active), AS (n = 13, disease control), and healthy controls (HC; n =...
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