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Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

21 Jun 2008

Abstract excerpt

As part of a biomarker discovery effort in peripheral blood, we acquired an immunological profile of cell-surface markers from healthy control and untreated subjects with relapsing-remitting MS (RRMS). Fresh blood from each subject was screened ex vivo using a panel of 50 fluorescently labelled monoclonal antibodies distributed amongst 56 pools of four antibodies each. From these 56 pools, we derived an...

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PMID: 18567923
DOI: 10.1093/brain/awn118

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