Article
Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.
Frontiers in cellular and infection microbiology - 1 Jan 2020
Harris Levelle D, Khayumbi Jeremiah, Ongalo Joshua, Sasser Loren E, Tonui Joan, Campbell Angela, Odhiambo Felix Hayara, Ouma Samuel Gurrion, Alter Galit, Gandhi Neel R, Day Cheryl L
Abstract excerpt
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), which leads to an estimated 1. 5 million deaths worldwide each year. Although the immune correlates of protection against Mtb infection and TB disease have not been well-defined, natural killer (NK) cells are increasingly recognized as a key component of the innate immune response to Mtb and as a link between innate and adaptive...
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