Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma.

Cancer immunology, immunotherapy : CII - 1 Jan 2022

Pánisová Elena, Lünemann Anna, Bürgler Simone, Kotur Monika, Lazarovici Julien, Danu Alina, Kaulfuss Meike, Mietz Juliane, Chijioke Obinna, Münz Christian, Busson Pierre, Berger Christoph, Ghez David, Azzi Tarik

Abstract excerpt

Around 30-50% of classical Hodgkin lymphoma (cHL) cases in immunocompetent individuals from industrialized countries are associated with the B-lymphotropic Epstein-Barr virus (EBV). Although natural killer (NK) cells exhibit anti-viral and anti-tumoral functions, virtually nothing is known about quantitative and qualitative differences in NK cells in patients with EBV+ cHL vs. EBV- cHL. Here, we prospectively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD56 Antigen
Share to Epstein-Barr Virus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GPI-Linked Proteins

Share to Herpesvirus 4, Human

Share to Hodgkin Disease

Share to Lysosomal-Associated Membrane Protein 1

Share to Receptors, IgG

Share to Rituximab

Source

Open in PubMed Open full text

Identifiers

PMID: 33993319
DOI: 10.1007/s00262-021-02956-x
PMCID: PMC8738354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma.PMID 33993319Read ↗

Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting.Semantic proximity Read ↗

The Evolving Knowledge on T and NK Cells in Classic Hodgkin Lymphoma: Insights into Novel Subsets Populating the Immune MicroenvironmentSemantic proximity Read ↗

Oncogenicity of EBV-infected natural killer T cells deteriorate EBV-related hemophagocytic lymphohistiocytosisSemantic proximity Read ↗

The utility of flow cytometry in differentiating NK/T cell lymphoma from indolent and reactive NK cell proliferations.Semantic proximity Read ↗

CD56dimCD16neg cells are responsible for natural cytotoxicity against tumor targets.Semantic proximity Read ↗

Human CD56bright NK Cells: An Update.Semantic proximity Read ↗

Poorly cytotoxic terminally differentiated CD56negCD16pos NK cells accumulate in Kenyan children with Burkitt lymphomasSemantic proximity Read ↗

Dominant cytotoxic NK cell subset within CLPD-NK patients identifies a more aggressive NK cell proliferationSemantic proximity Read ↗

Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers.Semantic proximity Read ↗

The arming of NK cells with Fc-engineered rituximab confers them specificity against CD20-expressing cellsSemantic proximity Read ↗

CD16+ as predictive marker for early relapse in aggressive B-NHL/DLBCL patientsSemantic proximity Read ↗

Increased natural killer cell expression of CD16, augmented binding and ADCC activity to rituximab among individuals expressing the FcγRIIIa-158 V/V and V/F polymorphismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.