Article
Decrease in cell counts and alteration of phenotype characterize peripheral NK cells of patients with anti-MDA5-positive dermatomyositis.
Clinica chimica acta; international journal of clinical chemistry - 15 Mar 2023
Lin Sang, Zhang Yinli, Cao Zhengyi, Xu Yuetong, Jin Qiwen, Chen Xixia, Shu Xiaoming, Lu Xin, Wang Guochun, Peng Qinglin
Abstract excerpt
OBJECTIVE: To investigate the levels and phenotypes of peripheral natural killer (NK) cells in anti-MDA5+ dermatomyositis (DM) patients, and their association with clinical features. METHODS: Peripheral NK cell counts (NKCCs) were retrospectively collected from 497 patients with idiopathic inflammatory myopathies and 60 healthy controls. Multi-color flow cytometry was used to determine the NK cell phenotypes in...
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