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Systematic post-translational modification profiling identifies molecular subtypes and therapeutic targets in ulcerative colitis: evidence from multi-omics integration

2026-05-08

Abstract excerpt

<title>Abstract</title> <p> Background Ulcerative colitis (UC) is a debilitating inflammatory bowel disease characterized by heterogeneous clinical presentations and variable treatment responses. Post-translational modifications (PTMs) coordinate immune signaling and mucosal barrier function, yet comprehensive PTM profiling to stratify UC patients and guide therapeutic decisions remains limited. Materials and M...

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Literature Corpus work
07b03c37-2d82-5664-93ce-70836a7d856c
DOI
10.21203/rs.3.rs-9497163/v1
Open publication

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Systematic post-translational modification profiling identifies molecular subtypes and therapeutic targets in ulcerative colitis: evidence from multi-omics integrationDOI 10.21203/rs.3.rs-9497163/v1
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